Article
Vitamin D receptor gene polymorphisms and distinct clinical phenotypes of hepatitis B carriers in Taiwan.
Genes and immunity - 1 Jan 2010
Huang Y-W, Liao Y-T, Chen W, Chen C-L, Hu J-T, Liu C-J, Lai M-Y, Chen P-J, Chen D-S, Yang S-S, Kao J-H
Abstract excerpt
Vitamin D exhibits immunomodulatory and antiproliferative effects through vitamin D receptor (VDR) in chronic infections and cancers. We genotyped the BsmI (rs1544410), ApaI (rs7975232) and TaqI (rs731236) polymorphisms of VDR gene in 250 Taiwanese chronic hepatitis B virus (HBV) carriers who were categorized into six phenotypes. After adjustment for age and sex, the frequencies of the VDR B/b, B/a, B/T, B/a/T in...
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