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Article

Genetic insights into hepatocellular carcinoma: the role of VDR FokI (rs2228570) and TaqI (rs731236) polymorphisms in Egyptian patients.

BMC medical genomics - 11 Feb 2026

Alrdahe Salma Saleh, Darwish Doaa Bahaa Eldin, Albalawi Aishah E, Omran Awatif M E, Almasaudi Nada Mohammed, Elsaid Afaf M, Youssef Magdy M

Abstract excerpt

BACKGROUND: Hepatocellular carcinoma (HCC) is the most dominant form of cancer. Its development is influenced by environmental exposures, lifestyle factors, and genetic predispositions. Beyond its classical function in skeleton and mineral metabolism, vitamin D also plays critical roles in immune regulation, tissue fibrosis, and tumor progression through interaction with the vitamin D receptor (VDR). This study...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 41668036
DOI: 10.1186/s12920-026-02322-9
PMCID: PMC12998322

Genes

VDR

Provenance

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Genetic insights into hepatocellular carcinoma: the role of VDR FokI (rs2228570) and TaqI (rs731236) polymorphisms in Egyptian patients.PMID 41668036Read ↗

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