Article
The Drosophila NCAM homolog Fas2 signals independently of adhesion.
Development (Cambridge, England) - 22 Jan 2020
Neuert Helen, Deing Petra, Krukkert Karin, Naffin Elke, Steffes Georg, Risse Benjamin, Silies Marion, Klämbt Christian
Abstract excerpt
The development of tissues and organs requires close interaction of cells. To achieve this, cells express adhesion proteins such as the neural cell adhesion molecule (NCAM) or its Drosophila ortholog Fasciclin 2 (Fas2). Both are members of the Ig-domain superfamily of proteins that mediate homophilic adhesion. These proteins are expressed as isoforms differing in their membrane anchorage and their cytoplasmic...
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