Article
Fas2EB112: a tale of two chromosomes.
G3 (Bethesda, Md.) - 7 May 2024
Finegan Tara M, Cammarota Christian, Mendoza Andrade Oscar, Garoutte Audrey M, Bergstralh Dan T
Abstract excerpt
The cell-cell adhesion molecule Fasciclin II (Fas2) has long been studied for its evolutionarily conserved role in axon guidance. It is also expressed in the follicular epithelium, where together with a similar protein, Neuroglian (Nrg), it helps to drive the reintegration of cells born out of the tissue plane. Remarkably, one Fas2 protein null allele, Fas2G0336, demonstrates a mild reintegration phenotype,...
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