Article
Genetic analysis of an overlapping functional requirement for L1- and NCAM-type proteins during sensory axon guidance in Drosophila.
Molecular and cellular neurosciences - 1 Jan 2005
Kristiansen Lars V, Velasquez Emma, Romani Susana, Baars Sigrid, Berezin Vladimir, Bock Elisabeth, Hortsch Michael, Garcia-Alonso Luis
Abstract excerpt
L1- and NCAM-type cell adhesion molecules represent distinct protein families that function as specific receptors for different axon guidance cues. However, both L1 and NCAM proteins promote axonal growth by inducing neuronal tyrosine kinase activity and are coexpressed in subsets of axon tracts in arthropods and vertebrates. We have studied the functional requirements for the Drosophila L1- and NCAM-type...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
