Article
Association of Complement Factor D and H Polymorphisms with Recurrent Pregnancy Loss.
International journal of molecular sciences - 18 Dec 2019
Cho Hee Young, Park Han Sung, Ko Eun Ju, Ryu Chang Soo, Kim Jung Oh, Kim Young Ran, Ahn Eun Hee, Lee Woo Sik, Kim Nam Keun
Abstract excerpt
Recurrent pregnancy loss (RPL) is defined as two or more consecutive pregnancy losses prior to 20 weeks of gestation, and the incidence of RPL is estimated at 1% of all pregnancies. While the etiologies of RPL are diverse, immune function is considered to be an important cause of RPL. In particular, the complement system is essential for stable development of the placenta and fetus. Moreover, complement factor D...
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