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Article

Polymorphisms in antithrombin and in tissue factor pathway inhibitor genes are associated with recurrent pregnancy loss.

Thrombosis and haemostasis - 1 Oct 2012

Guerra-Shinohara Elvira M, Bertinato Juliano Felix, Tosin Bueno Carolina, Cordeiro da Silva Kelma, Burlacchini de Carvalho Mário Henrique, Pulcineli Vieira Francisco Rossana, Zugaib Marcelo, Cerda Alvaro, Morelli Vânia Maris

Abstract excerpt

Recurrent pregnancy loss (RPL) is a multifactorial condition. The effect of antithrombin (SERPINC1), protein C (PROC), thrombomodulin (THBD) and tissue factor pathway inhibitor (TFPI) single nucleotide polymorphisms (SNPs) on the risk of RPL is thus far unknown. Our objective was to determine the association of SNPs in the above mentioned genes with RPL. We included 117 non-pregnant women with three or more...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22918506
DOI: 10.1160/TH12-03-0177

Genes

TFPI
PROC
SERPINC1
THBD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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