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Article

The outer dynein arm assembly factor CCDC103 forms molecular scaffolds through multiple self-interaction sites.

Cytoskeleton (Hoboken, N.J.) - 1 Jan 2020

King Stephen M, Patel-King Ramila S

Abstract excerpt

CCDC103 is a small protein with unusual biophysical properties that is required for outer dynein arm assembly on ciliary axonemes. Mutations in both human and zebrafish CCDC103 proteins lead to primary ciliary dyskinesia. Previous studies revealed that this protein can oligomerize and appears to be arrayed along the entire length of the ciliary axoneme. CCDC103 also binds purified microtubules directly and indeed...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 31858719
DOI: 10.1002/cm.21591
PMCID: PMC7002230

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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