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Article

XRCC1 variants do not represent a risk for dermatomyositis and systemic lupus erythematosus in Bulgarian patients.

Acta dermatovenerologica Alpina, Pannonica, et Adriatica - 1 Dec 2019

Kamenarska Zornitsa, Hristova Maria, Dodova Rumyana, Vinkov Anton, Kaneva Radka, Pozharashka Joana, Dourmishev Lyubomir

Abstract excerpt

INTRODUCTION: Systemic lupus erythematosus (SLE) and dermatomyositis (DM) share a similar pathogenesis, and genetic, hormonal, and environmental factors are known to trigger the autoimmune process. The X-ray repair cross-complementing genes (XRCC1 and XRCC3) are known to play a central role in mammalian DNA repair processes. Evidence suggests that impaired DNA repair efficiency is implicated in the development of...

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PMID: 31855267

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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