Article
Association between XRCC3 Thr241Met SNP and systemic lupus erythematosus in Han Chinese patients in Taiwan, and a meta-analysis of healthy populations.
Journal of clinical laboratory analysis - 1 Mar 2014
Chen Yng-Tay, Chen Shih-Yin, Lin Ying-Ju, Huang Chung-Ming, Chang Yuan-Yen, Tsai Fuu-Jen
Abstract excerpt
BACKGROUND: X-ray repair cross-complementing group 3 (XRCC3) plays a crucial role in mammalian DNA repair processes. The polymorphism of XRCC3, rs861539 (Thr > Met at codon 241), is common in populations worldwide. This study analyzed the relationship between this functional single nucleotide polymorphism and systemic lupus erythematosus (SLE) in the Han Chinese population in Taiwan (HC-TW). METHODS: Genotyping...
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