XRCC1 Arg399Gln gene polymorphism and the risk of systemic lupus erythematosus in the Polish population.

doi:10.1089/dna.2011.1246

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Article

XRCC1 Arg399Gln gene polymorphism and the risk of systemic lupus erythematosus in the Polish population.

DNA and cell biology - 1 Jan 2012

Warchoł Teresa, Mostowska Adriana, Lianeri Margarita, Lącki Jan K, Jagodziński Paweł P

Abstract excerpt

It has been shown that DNA repair is reduced in patients with systemic lupus erythematosus (SLE) and that the X-ray repair cross-complementing (XRCC1) Arg399Gln (rs25487) polymorphism may contribute to DNA repair. We evaluated the frequency of the XRCC1 Arg399Gln substitution in patients with SLE (n=265) and controls (n=360) in a sample of the Polish population. The odds ratio (OR) for SLE patients with the...

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PMID: 21682595
DOI: 10.1089/dna.2011.1246
PMCID: PMC3246417

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XRCC1

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