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Article

Lack of correlation between X-ray repair cross-complementing group 1 gene polymorphisms and the susceptibility to colorectal cancer in a Malaysian cohort.

European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Nov 2017

Lau Tze-Pheng, Lian Lay-Hoong, Cheah Phaik-Leng, Looi Lai-Meng, Roslani April C, Goh Khean-Lee, Lee Ping-Chin, Chua Kek-Heng

Abstract excerpt

X-ray repair cross-complementing group 1 (XRCC1) is one of the key components in the base excision repair pathway that repairs erroneous DNA lesions and removes nonbulky base adducts for the maintenance of genome integrity. Studies have revealed that differences in individual DNA repair capacity can impact the interindividual variation in cancer susceptibility, tumour aggressiveness and treatment response. The...

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PMID: 28059856
DOI: 10.1097/CEJ.0000000000000336

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XRCC1

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Lack of correlation between X-ray repair cross-complementing group 1 gene polymorphisms and the susceptibility to colorectal cancer in a Malaysian cohort.PMID 28059856Read ↗

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