Article
Platelet-derived β2m regulates age related monocyte/macrophage functions.
Aging - 18 Dec 2019
Hilt Zachary T, Ture Sara K, Mohan Amy, Arne Allison, Morrell Craig N
Abstract excerpt
Platelets have central roles in both immune responses and development. Stimulated platelets express leukocyte adhesion molecules and release numerous immune modulatory factors that recruit and activate leukocytes, both at the sites of activation and distantly. Monocytes are innate immune cells with dynamic immune modulatory functions that change during the aging process, a phenomenon termed "inflammaging". We...
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