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Article

The significance of macrophage polarization subtypes for animal models of tissue fibrosis and human fibrotic diseases

6 Feb 2015

Abstract excerpt

The systemic and organ-specific human fibrotic disorders collectively represent one of the most serious health problems world-wide causing a large proportion of the total world population mortality. The molecular pathways involved in their pathogenesis are complex and despite intensive investigations have not been fully elucidated. Whereas chronic inflammatory cell infiltration is universally present in fibrotic...

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PMID: 25852818
DOI: 10.1186/s40169-015-0047-4

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