Article
Association of Functional Polymorphisms of KIR3DL1/DS1 With Behçet's Disease.
Frontiers in immunology - 1 Jan 2019
Castaño-Núñez Ángel, Montes-Cano Marco-Antonio, García-Lozano José-Raúl, Ortego-Centeno Norberto, García-Hernández Francisco-José, Espinosa Gerard, Graña-Gil Genaro, Sánchez-Bursón Juan, Juliá María-Rosa, Solans Roser, Blanco Ricardo, Barnosi-Marín Ana-Celia, Gómez de la Torre Ricardo, Fanlo Patricia, Rodríguez-Carballeira Mónica, Rodríguez-Rodríguez Luis, Camps Teresa, Castañeda Santos, Alegre-Sancho Juan-Jose, Martín Javier, González-Escribano María-Francisca
Abstract excerpt
Behçet's disease (BD) is an immune-mediated vasculitis related to imbalances between the innate and adaptive immune response. Infectious agents or environmental factors may trigger the disease in genetically predisposed individuals. HLA-B51 is the genetic factor stronger associated with the disease, although the bases of this association remain elusive. NK cells have also been implicated in the etiopathogenesis...
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