Article
Is Behçet's disease a 'class 1-opathy'? The role of HLA-B*51 in the pathogenesis of Behçet's disease.
Clinical and experimental immunology - 1 Jan 2018
Giza M, Koftori D, Chen L, Bowness P
Abstract excerpt
The association between carriage of the human leucocyte antigen (HLA)-B*51 allele and development of Behçet's disease (BD) has been known since the early 1970s, but the exact mechanisms responsible for its role in pathogenesis remain much-debated. In an effort to explain the disease process, it has been suggested that BD constitutes one of a newly termed group of diseases, the 'MHC-I-opathies'. Other...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.