Article
KIR3DL1/S1 Allotypes Contribute Differentially to the Development of Behçet Disease.
Journal of immunology (Baltimore, Md. : 1950) - 15 Sept 2019
Petrushkin Harry, Norman Paul J, Lougee Emma, Parham Peter, Wallace Graham R, Stanford Miles R, Fortune Farida
Abstract excerpt
Behçet disease is a chronic, relapsing-remitting autoinflammatory syndrome with a strong HLA-B*51 association. In this paper, we describe a human cohort of 267 individuals with Behçet disease and 445 matched controls from a tertiary referral center in the U.K. HLA-B*51 was confirmed as a genetic risk factor in this group (p = 0.0006, Bonferroni-Dunn correction for multiple testing [Pc] = 0.0192, odds ratio [OR]...
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