Intrinsic and Extrinsic Factors for Natural Killer Cells and Their Involvement in Behcet Disease

Abstract excerpt

Behcet disease (BD) is an inflammatory disorder with manifestation in mucosal tissues. Unlike autoimmune diseases that generate autoantibodies, BD is believed to be an autoinflammatory disease triggered by innate immune cells rather than adaptive cells. Hyperactivation of neutrophils causes vasculitis and thrombosis, and they migrate into cutaneous and ocular lesions. Dominance of M1 macrophages promotes the diffe...

Topics

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• Aminopeptidases
• Antigen Presentation
• Behcet Syndrome
• Genetic Predisposition to Disease
• HLA-B Antigens
• Minor Histocompatibility Antigens
• Ocular Diseases and Behçet’s Syndrome
• Risk Factors

Identifiers and source

Literature Corpus work

ab85dd7e-ba18-5e67-85fa-41fc94785f9c

DOI

10.20944/preprints202603.0770.v1