Article
Genetics and immunodysfunction underlying Behçet's disease and immunomodulant treatment approaches.
Journal of immunotoxicology - 1 Dec 2017
Salmaninejad Arash, Gowhari Arezoo, Hosseini Seyedmojtaba, Aslani Saeed, Yousefi Meysam, Bahrami Tayyeb, Ebrahimi Masoume, Nesaei Abolfazl, Zal Masoud
Abstract excerpt
Behçet's disease (BD) is a chronic autoimmune condition primarily prevalent in populations along the Mediterranean Sea. The exact etiology of BD has not been fully explained yet, but the disease occurrence is associated with a genetic factor, human leukocyte antigen (HLA)-B51 antigen. Among the various immunodysfunctions that are found in BD, patients are increased neutrophil motility and superoxide production,...
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