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Article

Evaluation of KIR3DL1/KIR3DS1 polymorphism in Behçet's disease.

Genes and immunity - 1 Dec 2016

Erer B, Takeuchi M, Ustek D, Tugal-Tutkun I, Seyahi E, Özyazgan Y, Duymaz-Tozkir J, Gül A, Kastner D L, Remmers E F, Ombrello M J

Abstract excerpt

The Behçet's disease (BD)-associated human leukocyte antigen (HLA) allele, HLA-B*51 (B*51), encodes a ligand for a pair of allelic killer immunoglobulin-like receptors (KIR) present on cytotoxic cells-KIR3DL1, which inhibits their cytotoxicity, and KIR3DS1, which activates their cytotoxic activity. We tested whether KIR-regulated mechanisms contribute to BD by testing for association of KIR3DL1/KIR3DS1 genotypes...

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 27708262
DOI: 10.1038/gene.2016.36
PMCID: PMC5590678

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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