Article
A comprehensive overview on the genetics of Behçet's disease.
International reviews of immunology - 1 Jan 2000
Mahmoudi Mahdi, Aslani Saeed, Meguro Akira, Akhtari Maryam, Fatahi Yousef, Mizuki Nobuhisa, Shahram Farhad
Abstract excerpt
Behçet's disease (BD) is a systemic and inflammatory disease, characterized mainly by recurrent oral and genital ulcers, eye involvement, and skin lesions. Although the exact etiopathogenesis of BD remains unrevealed, a bulk of studies have implicated the genetic contributing factors as critical players in disease predisposition. In countries along the Silk Road, human leukocyte antigen (HLA)-B51 has been...
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