Article
Expression Quantitative Trait Loci (eQTL) Analysis in Cancer.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2020
Liu Yaoming, Ye Youqiong, Gong Jing, Han Leng
Abstract excerpt
Expression quantitative trait loci (eQTL) analysis links variations in gene expression levels to genotypes. Analyzing both cis- and trans-eQTLs from tumor samples can provide an intermediate phenotype between genetic variation and complex traits to better understand how risk alleles contribute to tumorigenesis and development. Here we describe a detailed workflow for identifying eQTLs in cancer using existing...
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