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Expression QTL-based analyses reveal the mechanisms underlying colorectal cancer predisposition.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Dec 2014

Zhang Jizhun, Jiang Kewei, Shen Zhanlong, Gao Zhidong, Lv Liang, Ye Yingjiang, Wang Shan

Abstract excerpt

Genome-wide association studies have identified many risk loci associated with colorectal cancer. Strategies integrating biological data sets with GWAS results will provide insights into the roles of risk single-nucleotide polymorphisms. We performed expression quantitative trait locus-based analyses using the information provided in The Cancer Genome Atlas. Analysis of the cis-expression quantitative trait loci...

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Colorectal Neoplasms
Computational Biology
Databases, Nucleic Acid
Gene Expression
Gene Expression Profiling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genome-Wide Association Study

Quantitative Trait Loci

Transcription, Genetic

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PMID: 25201067
DOI: 10.1007/s13277-014-2583-8

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MYC

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