Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Matrix eQTL: ultra fast eQTL analysis via large matrix operations.

Bioinformatics (Oxford, England) - 15 May 2012

Shabalin Andrey A

Abstract excerpt

MOTIVATION: Expression quantitative trait loci (eQTL) analysis links variations in gene expression levels to genotypes. For modern datasets, eQTL analysis is a computationally intensive task as it involves testing for association of billions of transcript-SNP (single-nucleotide polymorphism) pair. The heavy computational burden makes eQTL analysis less popular and sometimes forces analysts to restrict their...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Algorithms
Share to Cystic Fibrosis
Share to Gene Expression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Models, Genetic

Share to Polymorphism, Single Nucleotide

Share to Quantitative Trait Loci

Share to Software

Source

Open in PubMed Open full text

Identifiers

PMID: 22492648
DOI: 10.1093/bioinformatics/bts163
PMCID: PMC3348564

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Matrix eQTL: ultra fast eQTL analysis via large matrix operations.PMID 22492648Read ↗

Introductory Methods for eQTL Analyses.Semantic proximity Read ↗

kruX: matrix-based non-parametric eQTL discovery.Semantic proximity Read ↗

RTeQTL: Real-Time Online Engine for Expression Quantitative Trait Loci Analyses.Semantic proximity Read ↗

Expression Quantitative Trait Loci (eQTL) Analysis in Cancer.Semantic proximity Read ↗

A scalable unified framework of total and allele-specific counts for cis-QTL, fine-mapping, and prediction.Semantic proximity Read ↗

eQTL.Semantic proximity Read ↗

PolyQTL: Bayesian multiple eQTL detection with control for population structure and sample relatedness.Semantic proximity Read ↗

FastMap: fast eQTL mapping in homozygous populations.Semantic proximity Read ↗

OmiGA: A Toolkit for Ultra-efficient Molecular Trait Analysis in Complex PopulationsSemantic proximity Read ↗

Fast and efficient QTL mapper for thousands of molecular phenotypes.Semantic proximity Read ↗

A model selection approach for expression quantitative trait loci (eQTL) mapping.Semantic proximity Read ↗

iFORM/eQTL: an ultrahigh-dimensional platform for inferring the global genetic architecture of gene transcripts.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.