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Article

Maternally inherited coronary heart disease is associated with a novel mitochondrial tRNA mutation.

BMC cardiovascular disorders - 16 Dec 2019

Zhang Zhenxiao, Liu Mingyang, He Jianshuai, Zhang Xiaotian, Chen Yuehua, Li Hui

Abstract excerpt

BACKGROUND: Coronary heart disease (CHD) is the most common cause of mortality globally, yet mitochondrial genetic mutations associated with CHD development remain incompletely understood. METHODS: The subjects from three Chinese families with LHON underwent clinical, genetic, molecular, and biochemical evaluations. Biochemical characterizations included measuring the effects of the15910C > T mutation on tRNAThr...

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Identifiers

PMID: 31842766
DOI: 10.1186/s12872-019-01284-4
PMCID: PMC6912950

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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