Article
DNAH17 is associated with asthenozoospermia and multiple morphological abnormalities of sperm flagella.
Annals of human genetics - 1 May 2020
Sha Yanwei, Wei Xiaoli, Ding Lu, Mei Libin, Huang Xianjing, Lin Shaobin, Su Zhiying, Kong Lingyuan, Zhang Yi, Ji Zhiyong
Abstract excerpt
BACKGROUND: Multiple morphological abnormalities of the sperm flagella (MMAF) is one kind of severe asthenozoospermia, which is caused by dysplastic development of sperm flagella. In our study, we sought to investigate the novel gene mutations leading to severe asthenozoospermia and MMAF. METHODS AND MATERIALS: The patient's spermatozoa were tested by Papanicolaou staining and transmission electron microscopy....
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