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Genetic diagnosis, sperm phenotype and ICSI outcome in case of severe asthenozoospermia with multiple morphological abnormalities of the flagellum.

Human reproduction (Oxford, England) - 18 Oct 2021

Ferreux Lucile, Bourdon Mathilde, Chargui Ahmed, Schmitt Alain, Stouvenel Laurence, Lorès Patrick, Ray Pierre, Lousqui Johanna, Pocate-Cheriet Khaled, Santulli Pietro, Dulioust Emmanuel, Toure Aminata, Patrat Catherine

Abstract excerpt

STUDY QUESTION: Are ICSI outcomes impaired in cases of severe asthenozoospermia with multiple morphological abnormalities of the flagellum (MMAF phenotype)? SUMMARY ANSWER: Despite occasional technical difficulties, ICSI outcomes for couples with MMAF do not differ from those of other couples requiring ICSI, irrespective of the genetic defect. WHAT IS KNOWN ALREADY: Severe asthenozoospermia, especially when...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 34529793
DOI: 10.1093/humrep/deab200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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