Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Stochastic Expansions Maintain the Clonal Stability of CD8+ T Cell Populations Undergoing Memory Inflation Driven by Murine Cytomegalovirus

9 Dec 2019

Abstract excerpt

Abstract CMV is an obligate and persistent intracellular pathogen that continually drives the production of highly differentiated virus-specific CD8+ T cells in an Ag-dependent manner, a phenomenon known as memory inflation. Extensive proliferation is required to generate and maintain inflationary CD8+ T cell populations, which are counterintuitively short-lived and typically exposed to limited amounts of Ag...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to Immune Cell Function and Interaction
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31818981
DOI: 10.4049/jimmunol.1900455

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Stochastic Expansions Maintain the Clonal Stability of CD8+ T Cell Populations Undergoing Memory Inflation Driven by Murine CytomegalovirusPMID 31818981Read ↗

Competition between T cells maintains clonal dominance during memory inflation induced by MCMVSemantic proximity Read ↗

Non-Hematopoietic Cells in Lymph Nodes Drive Memory CD8 T Cell Inflation during Murine Cytomegalovirus InfectionSemantic proximity Read ↗

Memory Inflation: Continuous Accumulation of Antiviral CD8+ T Cells Over TimeSemantic proximity Read ↗

Cytomegalovirus Infection and Memory T Cell InflationSemantic proximity Read ↗

Sustained CD8+ T cell memory inflation after infection with a single-cycle cytomegalovirus.Semantic proximity Read ↗

Evolution of diverse antiviral CD8+ T cell populations after murine cytomegalovirus infectionSemantic proximity Read ↗

Tcf1+ cells are required to maintain the inflationary T cell pool upon MCMV infection.Semantic proximity Read ↗

A New Model for CD8+ T Cell Memory Inflation Based upon a Recombinant Adenoviral VectorSemantic proximity Read ↗

Stochastic Episodes of Latent Cytomegalovirus Transcription Drive CD8 T-Cell "Memory Inflation" and Avoid Immune Evasion.Semantic proximity Read ↗

Competition for antigen at the level of the APC is a major determinant of immunodominance during memory inflation in murine cytomegalovirus infection.Semantic proximity Read ↗

Evolution of Cytomegalovirus-Responsive T Cell Clonality following Solid Organ Transplantation.Semantic proximity Read ↗

The CMV-encoded G protein-coupled receptors M33 and US28 play pleiotropic roles in immune evasion and alter host T cell responsesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.