Dissimilar Trypanosoma cruzi genotype-specific serological profile assessed by Chagas-Flow ATE IgG1 upon benznidazole etiological treatment of chronic Chagas disease.

doi:10.1371/journal.pntd.0012487

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Dissimilar Trypanosoma cruzi genotype-specific serological profile assessed by Chagas-Flow ATE IgG1 upon benznidazole etiological treatment of chronic Chagas disease.

PLoS neglected tropical diseases - 1 Sept 2024

Alessio Glaucia Diniz, Silvestrini Carolina Malheiros Araújo, Elói-Santos Silvana Maria, Gontijo Eliane Dias, Sales Júnior Policarpo Ademar, Vitelli-Avelar Danielle Marchetti, Sathler-Avelar Renato, Wendling Ana Paula Barbosa, Teixeira-Carvalho Andréa, de Lana Marta, Martins-Filho Olindo Assis

Abstract excerpt

The present study aimed to verify the impact of etiological treatment on the genotype-specific serological diagnosis of chronic Chagas disease patients (CH), using the Chagas-Flow ATE IgG1 methodology. For this purpose, a total of 92 serum samples from CH, categorized as Not Treated (NT, n = 32) and Benznidazole-Treated (Bz-T, n = 60), were tested at Study Baseline and 5Years Follow-up. At Study Baseline, all...

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PMID: 39269987
DOI: 10.1371/journal.pntd.0012487
PMCID: PMC11423996

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