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Article

A novel duplication frameshift mutation in the BAG3 gene in a patient with dilated cardiomyopathy.

BMC cardiovascular disorders - 18 Mar 2026

Zhang Wei, Xu Kaihang, Liu Shiguang, Chen Juan, Jiang Hua

Abstract excerpt

BACKGROUND/OBJECTIVES: Dilated cardiomyopathy (DCM) is characterized by heart failure and cardiac dilation, distinguishing it from ischemic and non-ischemic heart diseases. To date, more than 50 genes have been identified as being associated with DCM. Mutations in the Bcl-2-associated athanogene 3 (BAG3) gene (NM_004281.4) play a significant role in DCM pathogenesis. However, further investigation is required for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41851620
DOI: 10.1186/s12872-026-05747-3
PMCID: PMC13122882

Genes

BAG3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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