Article
Tuning and controlling gene expression noise in synthetic gene networks.
Nucleic acids research - 1 May 2010
Murphy Kevin F, Adams Rhys M, Wang Xiao, Balázsi Gábor, Collins James J
Abstract excerpt
Synthetic gene networks can be used to control gene expression and cellular phenotypes in a variety of applications. In many instances, however, such networks can behave unreliably due to gene expression noise. Accordingly, there is a need to develop systematic means to tune gene expression noise, so that it can be suppressed in some cases and harnessed in others, e.g. in cellular differentiation to create...
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