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Article

Dynamic and tunable metabolite control for robust minimal-equipment assessment of serum zinc.

Nature communications - 4 Dec 2019

McNerney Monica P, Michel Cirstyn L, Kishore Krishi, Standeven Janet, Styczynski Mark P

Abstract excerpt

Bacterial biosensors can enable programmable, selective chemical production, but difficulties incorporating metabolic pathways into complex sensor circuits have limited their development and applications. Here we overcome these challenges and present the development of fast-responding, tunable sensor cells that produce different pigmented metabolites based on extracellular concentrations of zinc (a critical...

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Identifiers

PMID: 31797936
DOI: 10.1038/s41467-019-13454-1
PMCID: PMC6892929

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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