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Cell-free DNA methylation biomarker for the diagnosis of papillary thyroid carcinoma

1 Mar 2023

Abstract excerpt

BACKGROUND: Cell-free DNA (cfDNA) is being explored as biomarker for non-invasive diagnosis of cancer. We aimed to establish a cfDNA-based DNA methylation marker panel to differentially diagnose papillary thyroid carcinoma (PTC) from benign thyroid nodule (BTN). METHODS: 220 PTC- and 188 BTN patients were enrolled. Methylation markers of PTC were identified from patients' tissue and plasma by reduced...

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PMID: 36868052
DOI: 10.1016/j.ebiom.2023.104497

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