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Article

Limited evolution of the yellow fever virus 17d in a mouse infection model.

Emerging microbes & infections - 1 Jan 2019

Kum Dieudonné Buh, Mishra Niraj, Vrancken Bram, Thibaut Hendrik Jan, Wilder-Smith Annelies, Lemey Philippe, Neyts Johan, Dallmeier Kai

Abstract excerpt

By infecting mice with the yellow fever virus vaccine strain 17D (YFV-17D; Stamaril®), the dose dependence and evolutionary consequences of neurotropic yellow fever infection was assessed. Highly susceptible AG129 mice were used to allow for a maximal/unlimited expansion of the viral populations. Infected mice uniformly developed neurotropic disease; the virus was isolated from their brains, plaque purified and...

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Source

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Identifiers

PMID: 31797751
DOI: 10.1080/22221751.2019.1694394
PMCID: PMC6896426

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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