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Article

Antigenic variants of yellow fever virus with an altered neurovirulence phenotype in mice.

Virology - 14 Apr 1997

Ryman K D, Xie H, Ledger T N, Campbell G A, Barrett A D

Abstract excerpt

The live-attenuated yellow fever (YF) vaccine virus, strain 17D-204, has long been known to consist of a heterologous population of virions. Gould et al. (J. Gen. Virol. 70, 1889-1894 (1989)) previously demonstrated that variant viruses exhibiting a YF wild-type-specific envelope (E) protein epitope are present at low frequency in the vaccine pool and were able to isolate representative virus variants with and...

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Identifiers

PMID: 9143294
DOI: 10.1006/viro.1997.8496

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