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Article

Bromocriptine improves glucose tolerance independent of circadian timing, prolactin, or the melanocortin-4 receptor.

American journal of physiology. Endocrinology and metabolism - 1 Jan 2020

Framnes-DeBoer Sarah N, Bakke Ellen, Yalamanchili Suma, Peterson Hannah, Sandoval Darleen A, Seeley Randy J, Arble Deanna M

Abstract excerpt

Bromocriptine, a dopamine D2 receptor agonist originally used for the treatment of hyperprolactinemia, is largely successful in reducing hyperglycemia and improving glucose tolerance in type 2 diabetics. However, the mechanism behind bromocriptine's effect on glucose intolerance is unclear. Here, we tested three hypotheses, that bromocriptine may exert its effects on glucose metabolism by 1) decreasing prolactin...

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Source

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Identifiers

PMID: 31794265
DOI: 10.1152/ajpendo.00325.2019
PMCID: PMC6985791

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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