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Article

Effects of cafeteria diet and caloric restriction on pituitary hormones and metabolic phenotype in male Wistar rats.

Endocrine - 1 Dec 2025

Kagios Christakis, Hetty Susanne, Hukema Fleur, Fanni Giovanni, Roman Erika, Eriksson Jan W

Abstract excerpt

PURPOSE: Obesity is associated with neuroendocrine and metabolic dysregulation, yet the underlying mechanisms remain incompletely understood. This study aimed to investigate how pituitary hormonal axes and peripheral hormones respond to a cafeteria diet or a calorie-restricted diet in rats. METHODS: Ten-week-old male Wistar rats (n = 36) were randomized (1:1:1) to one of three diets for 12 weeks: an ad libitum...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41091300
DOI: 10.1007/s12020-025-04448-9
PMCID: PMC12708789

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