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Article

Indolent course of brainstem tumors with K27M-H3.3 mutation.

Pediatric blood & cancer - 1 Mar 2020

Baroni Lorena V, Solano-Paez Palma, Nobre Liana, Michaeli Orli, Hawkins Cynthia, Laughlin Suzanne, Bartels Ute, Ramaswamy Vijay, Bouffet Eric

Abstract excerpt

Diffuse intrinsic pontine glioma (DIPG) is characterized by a short history of brainstem symptoms and well-known magnetic resonance imaging features with a fatal outcome. However, we report three unusual cases of brainstem tumors with an initial indolent and protracted course, which subsequently developed the classical imaging and clinical features of DIPG. Our findings support this notion that K27M is an early...

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PMID: 31793190
DOI: 10.1002/pbc.28102

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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