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Article

CD39+ regulatory T cells modulate the immune response to carbamazepine in HLA-B*15:02 carriers.

Immunobiology - 1 Jan 2020

Shen Meixin, Lim Joey Ming Er, Chia Cheryl, Ren Ee Chee

Abstract excerpt

The HLA-B*15:02 allele is associated with an increased risk of developing carbamazepine (CBZ)-induced Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). Many studies, however, have demonstrated that a large majority of HLA-B*15:02 individuals are unlikely to develop the adverse drug reaction while on CBZ. This phenomenon suggests that other factors that modulate the allergic immune response,...

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Source

Identifiers

PMID: 31784043
DOI: 10.1016/j.imbio.2019.11.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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