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Article

Cross-talk between SIM2s and NFκB regulates cyclooxygenase 2 expression in breast cancer.

Breast cancer research : BCR - 29 Nov 2019

Wyatt Garhett L, Crump Lyndsey S, Young Chloe M, Wessells Veronica M, McQueen Cole M, Wall Steven W, Gustafson Tanya L, Fan Yang-Yi, Chapkin Robert S, Porter Weston W, Lyons Traci R

Abstract excerpt

BACKGROUND: Breast cancer is a leading cause of cancer-related death for women in the USA. Thus, there is an increasing need to investigate novel prognostic markers and therapeutic methods. Inflammation raises challenges in treating and preventing the spread of breast cancer. Specifically, the nuclear factor kappa b (NFκB) pathway contributes to cancer progression by stimulating proliferation and preventing...

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Identifiers

PMID: 31783895
DOI: 10.1186/s13058-019-1224-y
PMCID: PMC6884910

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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