Article
Characterization of NCC-RbC-51, an RB cell line isolated from a metastatic site.
Histochemistry and cell biology - 1 Feb 2020
Ravishankar Hemanth, Mangani Abubakar Siddiq, Shankar M Bhavani, Joshi Mayur, Devasena T, Parameswaran Sowmya, Subramaniam Krishnakumar
Abstract excerpt
Retinoblastoma (RB) is a childhood eye tumor, caused by the RB1 gene mutation. Since RB is a rapidly proliferating tumor, the patient presents with a Group-D/E tumor at the time of diagnosis. Enucleation is preferred in most unilateral cases to prevent metastasis. Various cell lines have been established to study the tumor's growth pattern and target the cancer cells. The commonly used cell lines are WERI-Rb-1...
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