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Dysfunctional missense variant of OAT10/SLC22A13 decreases gout risk and serum uric acid levels

28 Nov 2019

Abstract excerpt

Organic anion transporter 10 (OAT10), also known as SLC22A13, has hitherto been identified as a urate transporter by in vitro analyses.1 Despite the reported expression of OAT10 on the apical membrane of the renal proximal tubular cells,1 the physiological impact of OAT10 on urate handling in humans remains to be elucidated. Accumulating evidence suggests that functional variants of already-characterised,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31780526
DOI: 10.1136/annrheumdis-2019-216044

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