Article
Association of vitamin D receptor gene polymorphisms with disc degeneration.
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society - 1 Mar 2020
Biczo Adam, Szita Julia, McCall Iain, Varga Peter Pal, Lazary Aron
Abstract excerpt
PURPOSE: Numerous candidate genes and single-nucleotide polymorphisms (SNPs) have been identified in the background of lumbar disc degeneration (LDD). However, in most of these underpowered studies, definitions of LDD are inconsistent; moreover, many of the findings have not been replicated and are contradictory. Our aim was to characterize LDD by well-defined phenotypes and possible endophenotypes and analyse...
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