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Article

Vitamin D receptor gene polymorphisms and lumbar disc degeneration: a systematic review and meta-analysis.

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society - 1 Jan 2017

Jiang Hua, Qin Zhilin, Zong Shaohui, He Maolin, Zhan Xinli, Xiao Zengming, Wei Qingjun

Abstract excerpt

PURPOSE: To examine the association between Vitamin D receptor (VDR) gene polymorphisms and lumbar disc degeneration (LDD) predisposition. METHODS: A comprehensive literature search was conducted to identify all the relevant studies. The allele/genotype frequencies were extracted from each study. We calculated the pooled odds ratios (ORs) and 95 % confidence intervals (CI) to assess the strength of the...

Topics

Genetic Predisposition to Disease
Humans
Intervertebral Disc Degeneration
Polymorphism, Genetic
Receptors, Calcitriol

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 27613009
DOI: 10.1007/s00586-016-4771-2

Genes

VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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