Article
The Role of Inducible NOS2 Gene Polymorphism in the Development of Essential Arterial Hypertension.
Bulletin of experimental biology and medicine - 1 Nov 2019
Topchieva L V, Balan O V, Korneeva V A, Malysheva I E
Abstract excerpt
The risk of essential arterial hypertension was assessed in carriers of the NOS2 gene variants (rs1800482 (-954G>C), rs3730017 (C>T)). In subjects carrying C allele (rs1800482), the risk for essential arterial hypertension developing was higher by 1.7 times (OR=1.712, 95%CI 1.07-2.74), while the presence of T-allele (rs3730017) had a protective effect (OR=0.304, 95%CI 0.192-0.482). In patients with essential...
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