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Article

Prevalence of mutations in Plasmodium falciparum genes associated with resistance to different antimalarial drugs in Nyando, Kisumu County in Kenya.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Mar 2020

Musyoka Kelvin B, Kiiru John N, Aluvaala Eva, Omondi Protus, Chege William K, Judah Terry, Kiboi Daniel, Nganga Joseph K, Kimani Francis T

Abstract excerpt

Resistance to the mainstay antimalarial drugs is a major concern in the control of malaria. Delayed Plasmodium falciparum parasite clearance has been associated with Single Nucleotide Polymorphisms (SNPs) in the kelch propeller region (K13). However, SNPs in the Pf-adaptor protein complex 2 mu subunit (Pfap2-mu), Pfcrt and Pfmdr1 are possible markers associated with multi-drug resistance. Here, we explored the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31756512
DOI: 10.1016/j.meegid.2019.104121

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