Identification of the PfK13 mutations R561H and P441L in the Democratic Republic of Congo.

doi:10.1016/j.ijid.2023.11.026

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Article

Identification of the PfK13 mutations R561H and P441L in the Democratic Republic of Congo.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Feb 2024

Mesia Kahunu Gauthier, Wellmann Thomsen Sarah, Wellmann Thomsen Louise, Muhindo Mavoko Hypolite, Mitashi Mulopo Patrick, Filtenborg Hocke Emma, Mandoko Nkoli Papy, Baraka Vito, Minja Daniel T R, Mousa Andria, Roper Cally, Mbongi Moke Destin, Mumba Ngoyi Dieudonné, Mukomena Sompwe Eric, Muyembe Tanfum Jean Jacques, Hansson Helle, Alifrangis Michael

Abstract excerpt

OBJECTIVES: Partial artemisinin resistance, mediated by Plasmodium falciparum K13 (PfK13) mutations, has been confirmed in certain areas of East Africa that are historically associated with high-level antimalarial resistance. The Democratic Republic of Congo (DRC) borders these areas in the East. This study aimed to determine the prevalence of resistance markers in six National Malaria Control Program...

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PMID: 38016502
DOI: 10.1016/j.ijid.2023.11.026

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