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Article

Phosphatidylinositol 3-kinase Glu545Lys and His1047Tyr Mutations are not Associated with T2D.

Current diabetes reviews - 1 Jan 2020

Elfaki Imadeldin, Mir Rashid, Abu-Duhier Faisel M, Khan Roaid, Sakran Mohammed

Abstract excerpt

BACKGROUND: Insulin resistance initiated in peripheral tissues induces type 2 diabetes (T2D). It occurs when insulin signaling is impaired. INTRODUCTION: Phosphatidylinositol 3-kinases (PI3K) are important for insulin signaling. Single nucleotide polymorphisms of the PI3K gene have been associated with T2D. METHODS: We have investigated the association of Glu545Lys and His1047Tyr mutations of...

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Identifiers

PMID: 31749428
DOI: 10.2174/1573399815666191015142201

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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