Article
Lack of association between UBE2E2 gene polymorphism (rs7612463) and type 2 diabetes mellitus in a Saudi population.
Acta biochimica Polonica - 1 Jan 2014
Alharbi Khalid Khalaf, Khan Imran Ali, Al-Sheikh Yazeed A, Alharbi Fawiziah Khalaf, Alharbi Fahad Khalaf, Al-Nbaheen May Salem
Abstract excerpt
The ubiquitin-conjugating enzyme E2E 2 (UBE2E2) gene plays an important role in insulin synthe-sis and secretion under conditions in which stress to the endoplasmic reticu-lum is increased in β-cells. In this case-control study, we have selected rs7612462 polymorphism within UBE2E2 gene to identi...
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