Article
Epidermal Growth Factor Receptor Mutations in Resectable Non-Small Cell Lung Cancer Patients and their Potential Role in the Immune Landscape.
Medical science monitor : international medical journal of experimental and clinical research - 20 Nov 2019
Xia Wei, Mao Wenjun, Chen Ruo, Lu Rongguo, Liu Feng, He Yijun, Wang Shengfei, Li Xiaomin, Zheng Mingfeng
Abstract excerpt
BACKGROUND The epidermal growth factor receptor (EGFR) is a therapeutic target for non-small cell lung cancer (NSCLC), but knowledge on gene mutations that contribute to NSCLC development and persistence is lacking. In this study, we investigated genetic variations in EGFR and their association with the clinical and pathological factors of NSCLC. MATERIAL AND METHODS Clinical cases (331 patients) and The Cancer...
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